Evolutionary and Expression Analysis of miR-#-5p and miR-#-3p at the miRNAs/isomiRs Levels

Figure 2

Scatter plots of miR-#-5p and miR-#-3p (a); homologous miRNAs and distribution of Spearman correlation coefficients (b). (a) Scatter plots of nucleotide substitution rates in the common miRNAs and their nondominant strands based on each position along miRNA (the conservation level was estimated based on nucleotide substitution rates along miRNA). (b) Scatter plots of nucleotide substitution between homologous miRNAs (miRNA gene family). miR-#-5p and miR-#-3p were compared and analyzed. The last figure indicates the distribution of Spearman correlation coefficient (ρ) across different miRNA gene families.