Evaluation of APP695 Transgenic Mice Bone Marrow Mesenchymal Stem Cells Neural Differentiation for Transplantation

Figure 2

Notch signaling was inhibited during differentiation of the MSCs. (a) The expression levels of Notch-1, NICD, and Hes5 were analyzed by western blot before the induction with β-ME. (b) The expression levels of Notch-1, NICD, and Hes5 after the induction with β-ME. The expression of β-actin was used as a loading control. (c, d, and e) The quantification of the expression levels of Notch-1, NICD, and Hes5 (mean ± SD; ). APP695 versus WT (before induction), ^*; APP695 versus WT (after induction), ^#.

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