Unsaturated Fatty Acids Supplementation Reduces Blood Lead Level in Rats
Table 2
Influence of dietary supplementation with olive oil or linseed oil or super lecithin on serum lipids and lipid transfer proteins in nonpoisoned rats and rats poisoned with lead.
Group of rats
Lipids
Proteins
Chol mmol/L
TG mmol/L
HDL-C mmol/L
HDL3-C mmol/L
HDL2-C mmol/L
Non HDL-C mmol/L
PLTP pmol/µl/hr
CETP pmol/µl/hr
Untreated ()
1.0 ± 0.23
1.04 ± 0.51
0.88 ± 0.23
0.45 ± 0.16
0.45 ± 0.07
0.62 ± 0.14
70.2 ± 23.1
28.7 ± 3.9
Olive oil ()
1.35 ± 0.25
1.02 ± 0.3
0.95 ± 0.21
0.50 ± 0.12
0.45 ± 0.18
0.4 ± 0.14b
82.3 ± 18.9
27.9 ± 5.1
Linseed oil ()
1.32 ± 0.15c
0.81 ± 0.29
0.8 ± 0.09
0.52 ± 0.07
0.28 ± 0.07a
0.53 ± 0.1
61.7 ± 10.9
31.8 ± 5.6
Super lecithin ()
1.57 ± 0.19
0.95 ± 0.25
0.95 ± 0.15
0.56 ± 0.10c
0.39 ± 0.10
0.62 ± 0.21
61.4 ± 11.2
34.4 ± 3.6b
Pb ()
1.43 ± 0.16
0.99 ± 0.64
0.93 ± 0.11
0.51 ± 0.06
0.42 ± 0.08
0.50 ± 0.12
74.3 ± 17.7
29.7 ± 8.3
Pb + olive oil ()
1.42 ± 0.15
1.11 ± 0.46
0.88 ± 0.25
0.44 ± 0.14
0.44 ± 0.16
0.54 ± 0.2
85.4 ± 14.2
28.7 ± 2.6
Pb + linseed oil ()
1.33 ± 0.12
0.81 ± 0.18
0.87 ± 0.13
0.51 ± 0.07
0.33 ± 0.13
0.42 ± 0.18
57.5 ± 13.6
27.9 ± 6.7
Pb + super lecithin ()
1.62 ± 0.26
1.11 ± 0.20
0.91 ± 0.17
0.57 ± 0.10
0.34 ± 0.10
0.70 ± 0.2y
60.1 ± 6.8z
34.1 ± 2.2
Results are presented as mean ± SD. Statistically significant differences: a, b; c in comparison to untreated rats; y, z in comparison to group of rats given lead acetate (Pb group). Chol: cholesterol; TG: triglycerides; HDL-C: high density cholesterol; HDL3-C: HDL3 cholesterol; HDL2-C: HDL2 cholesterol; non HDL-C: non HDL cholesterol; PLTP: phospholipid transfer protein; CETP: cholesteryl ester transfer protein.