Effects of Etanercept against Transient Cerebral Ischemia in Diabetic Rats

Figure 2

Effects of ETN on infarction induced by cerebral ischemia in non-DM and DM rat brains. (a) Representative coronal brain sections of the non-DM rats and the ETN group stained by TTC for various ETN administration conditions after reperfusion. (b) Representative coronal brain sections of the DM rats and the ETN group stained by TTC under various ETN administration conditions after reperfusion. The closed and open columns are the vehicle and ETN groups, respectively. Scale bar = 5 mm. Data are the means ± SDs (–6 per time point). and 0.01 for statistical significance compared with the vehicle group. DM, diabetes mellitus; ETN, etanercept; TTC, 2,3,5-triphenyl tetrazolium chloride.

(a) Non-DM

(b) DM