The Role of Enteral Nutrition in Patients with Inflammatory Bowel Disease: Current Aspects

Table 3

Enteral nutrition (elemental and polymeric diet) on induction of remission in patients with Crohn’s disease.

Author/reference	Number of patients	Diets compared	Outcomes/measurements	Results	Conclusion
Greenberg et al. [28]	51	TPN versus formula diet via NG versus partial parenteral and oral food	Relapse rates, weight, albumin, arm circumference, and triceps skinfold thickness	Clinical remission in 71% of parenteral group, 60% of partial parenteral group, and 58% defined formula group	In patients with active CD bowel rest is not a major factor in achieving a remission during nutritional support and did not influence outcome during one-year follow-up
Jones [29]	36	TPN versus elemental for induction of remission in CD	CDAI, ESR, and serum albumin	Both were successful with no significant differences.; Elemental diet is cheaper, safer, and simpler	The use of EN followed by a personal food exclusion diet is an effective long-term therapeutic strategy for CD
Esaki et al. [30]	145	Enteral nutrition versus nonenteral (elemental or polymeric) nutrition	Rate of relapse based on CDAI scores	The rate of recurrence was higher in the nonenteral nutrition group than in the EN group	Among patients with CD under maintenance EN, the risk of recurrence differs according to the disease type and location. EN alone is insufficient for patients with penetrating type or with colonic involvement