Research Article
Biphasic Regulation of Lipid Metabolism: A Meta-Analysis of Icodextrin in Peritoneal Dialysis
Table 4
Effect of icodextrin use on lipid profiles (cross-sectional studies).
| Factor | Number of studies | Heterogeneity test | Weighted mean difference | | | value | Model of meta | Mean | [95% CI] | value |
| APO-B (mg/dL) | 2 | 2.45 | 59.30% | 0.117 | R | | | 0.855 | Total cholesterol (mmol/L) | 6 | 1.17 | <0.01% | 0.947 | F | | | 0.937 | Triglycerides (mmol/L) | 5 | 4.68 | 14.5% | 0.322 | F | | | 0.001 | HDL-C (mmol/L) | 4 | 9.27 | 67.60% | 0.026 | R | | | 0.223 | LDL-C (mmol/L) | 2 | 0.09 | <0.01% | 0.77 | F | | | 0.096 | VLDL-C (mmol/L) | 2 | 0.01 | <0.01% | 0.916 | F | | | 0.915 |
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Note: the value was less than 0.05, and the WMD was considered statistically significant. Model of meta: F: Fixed, R: Random.
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