Research Article
Biphasic Regulation of Lipid Metabolism: A Meta-Analysis of Icodextrin in Peritoneal Dialysis
Table 7
Effect of icodextrin on lipid profiles in diabetes patients (in subgroups of duration).
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Factor | Duration | Number of studies | Heterogeneity test | Weighted mean difference | | | value | Model of meta | Mean | [95% CI] | value |
| Total cholesterol (mmol/L) | <6 month | 2 | 1.06 | 5.60% | 0.303 | F | | | 0.027 | ≥6 month | 2 | 2.05 | 51.20% | 0.152 | F | | | 0.087 |
| Triglycerides (mmol/L) | <6 month | 2 | 1.63 | 38.60% | 0.202 | F | | | 0.244 | ≥6 month | 2 | 0.49 | <0.01% | 0.483 | F | | | 0.467 |
| HDL-C (mmol/L) | <6 month | 2 | 0.17 | <0.01% | 0.677 | F | | | 0.845 | ≥6 month | 2 | 0.09 | <0.01% | 0.759 | F | | | 0.002 |
| LDL-C (mmol/L) | <6 month | 2 | 2.23 | 55.10% | 0.135 | F | | | 0.057 | ≥6 month | 2 | 1.45 | 31.00% | 0.228 | F | | | 0.171 |
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Note: the value was less than 0.05, and the WMD was considered statistically significant. Model of meta: F: Fixed, R: Random.
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