Hypoglycemic and Antidiabetic Effect of Pleurotus sajor-caju Aqueous Extract in Normal and Streptozotocin-Induced Diabetic Rats
Table 1
Initial screening (BG study) of hypoglycemic effect of graded doses of PSC aqueous extract in normal rats (mean ± SD).
Experimental animals
Treatment
Blood glucose levels (mmol/L)
Pretreatment level
Posttreatment level
FBG
2 h
4 h
6 h
Normal (control)
Distilled water
5.0 ± 0.1
4.9 ± 0.1
4.8 ± 0.1
4.7 ± 0.1
Normal (treated)
Metformin (150 mg/kg)
5.3 ± 0.3
4.6 ± 0.1
4.2 ± 0.1
4.0 ± 0.1
Normal (treated)
PSCE (500 mg/kg)
5.1 ± 0.2
4.8 ± 0.1
4.6 ± 0.2
4.5 ± 0.1
Normal (treated)
PSCE (750 mg/kg)
5.1 ± 0.2
4.4 ± 0.2
4.1 ± 0.3
3.9 ± 0.2
Normal (treated)
PSCE (1000 mg/kg)
5.2 ± 0.3
4.6 ± 0.2
4.3 ± 0.1
4.1 ± 0.1
as compared to normal control group (distilled water). as compared to normal treated group (metformin 150 mg/kg). PSCE, Pleurotus sajor-caju aqueous extract.
