Research Article

Antiherpes Activity and Skin/Mucosa Distribution of Flavonoids from Achyrocline satureioides Extract Incorporated into Topical Nanoemulsions

Table 3

Antiherpes activity of ASE- and QCT-loaded nanoemulsions and their controls.

CC50 (g/mL)IC50 (g/mL)SIa

ASE15.71 ± 8.6114.07 ± 3.461
ASE-nanoemulsion11.25 ± 0.481.40 ± 0.88*8

QCT25.34 ± 6.887.93 ± 1.533
QCT-nanoemulsion138.52 ± 33.36*9.51 ± 5.9814

SI: CC50/IC50; *significant statistical differences were determined by Tukey’s test ( < 0.05).