Relationship of Baseline Hemoglobin Level with Serum Ferritin, Postphlebotomy Hemoglobin Changes, and Phlebotomy Requirements among HFE C282Y Homozygotes

Table 1

Baseline characteristics of the patients () according to HFE genotype.

Genotype groups	Age	SF (μg/L)	TS (%)	Hb (g/L)
Males ( = 142)
C282Y/C282Y ( = 124)	47.3 ± 13.0	979 ± 688	78.2 ± 15.5	150.4 ± 10.1
	(20–84)	(316–4000)	(39–100)	(124–172)
C282Y/H63D ( = 18)	51.0 ± 9.5	632 ± 179	59.2 ± 15.4	153.2 ± 6.7
	(29–69)	(326–967)	(31–88)	(143–169)
Reference ranges		15–300]	≤50%]	130–165]
Females ( = 72)
C282Y/C282Y	54.6 ± 10.3	646 ± 496	74.5 ± 16.8	138.2 ± 8.1
	(31–71)	(210–3100)	(29–100)	(116–156)
Reference ranges		15–200]	≤45%]	115–155]

Results are mean ± SD; values in parentheses are range: minimum–maximum.
Age at the start of treatment.
, comparison between male C282Y/H63D and male C282Y/C282Y.
, comparison between female C282Y/C282Y and male C282Y/C282Y.
Hb: hemoglobin; SF: serum ferritin; TS: transferrin saturation.