Relationship of Baseline Hemoglobin Level with Serum Ferritin, Postphlebotomy Hemoglobin Changes, and Phlebotomy Requirements among HFE C282Y Homozygotes
Table 4
Baseline and treatment characteristics of hemoglobin subgroups of C282Y homozygotes by gender.
Subgroups
Age
SF (μg/L)
TS (%)
Interval
Post-SF
Males
Low SF/high Hb
43.4 ± 13.3
640 ± 169
74.1 ± 15.2
15.7 ± 6.12
42.1 ± 5.23
Low SF/low Hb
47.2 ± 10.6
685 ± 167
72.5 ± 14.5
16.1 ± 4.10
42.3 ± 4.33
value
0.18
0.25
0.68
0.71
0.83
High SF/high Hb
50.5 ± 13.7
1728 ± 931
80.9 ± 12.9
13.6 ± 4.08
42.0 ± 3.76
High SF/low Hb
53.9 ± 12.2
1647 ± 819
91.9 ± 6.6
14.4 ± 3.41
41.7 ± 4.32
value
0.43
0.80
0.002
0.52
0.73
Females
Low SF/high Hb
54.9 ± 10.2
466 ± 164
75.7 ± 16.4
15.8 ± 5.19
41.9 ± 5.96
Low SF/low Hb
53.5 ± 11.4
480 ± 161
68.6 ± 15.0
17.0 ± 5.03
42.9 ± 4.51
value
0.72
0.62
0.31
0.39
0.48
High SF/high Hb
51.7 ± 11.0
1872 ± 375
75.7 ± 24.4
18.7 ± 4.04
43.7 ± 2.31
High SF/low Hb
57.8 ± 7.1
1513 ± 683
91.6 ± 3.8
16.3 ± 4.26
44.1 ± 3.18
value
0.30
0.26
0.18
0.40
0.82
Results are mean ± SD. Interval: the time interval between the penultimate phlebotomy and the last phlebotomy. Post-SF: posttreatment SF.
