Functional and Structural Abnormalities in Deferoxamine Retinopathy: A Review of the Literature

Figure 9

Serial color photos and OCT scans of a patient with speckled pattern during a 3-year follow-up. (a) At baseline examination, pigmented material was visible in the fovea, with small yellow flecks extending beyond the vascular arcades. On OCT scan, granular hyperreflective deposits were detected in the subretinal space, extending into the outer plexiform layer and interrupting the overlying external limiting membrane. (b) After 1 year, initial RPE atrophy was visible around the fovea, with disruption of the outer retinal layers on OCT scan. (c) At year 3, frank RPE atrophy developed in the macula; OCT scan showed atrophy of the outer retinal layers and RPE, as well as thinning of the inner retina.

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