Analysis of the Expression and Polymorphism of APOE, HSP, BDNF, and GRIN2B Genes Associated with the Neurodegeneration Process in the Pathogenesis of Primary Open Angle Glaucoma
Table 1
The clinical parameters characteristic of open angle glaucoma (POAG) patients and control groups.
Parameters
Patient groups
Control groups
Number
Gender (male/female)
98/265
174/232
Hypertension
218
132
Low blood pressure
75
54
Vascular disease
124
92
Diabetes mellitus type 2
70
104
Mean ± SD
Age (years)
73 ± 10
64 ± 16
Intraocular pressure, IOP (mmHg)
12.82 ± 2.9
11.9 ± 1.9
Cup disk ratio (c/d) right eye/left eye
0.74 ± 0.15/0.74 ± 0.27
PNM
Rim area (RA) right eye/left eye
1.45 ± 3.57/1.29 ± 1.07
PNM
Retinal nerve fiber layer (RNFL) right eye/left eye