Research Article
Vitamin D Status in Women with Gestational Diabetes Mellitus during Pregnancy and Postpartum
Table 1
Characteristics of study subjects.
| | Parameters | GDM ( = 47) | Controls ( = 29) | |
| | Pregestational parameters | | | | | Age (years) | 33 [28–35] | 31 [28–33] | NS | | BMI (kg/m2) | 24.45 [22.68–28.91] | 21.11 [20.44–24.77] | 0.014 | | History of previous GDM | 12.8% | 0% | 0.0491 | | Family history of DM | 78.7% | 17.2% | 0.0018 | | Midgestational parameters (24–30th weeks of gestation) | | | | | FPG (mmol/L) | 4.8 [4.5–5.2] | 4.1 [4.0–4.4] |
<0.001 | | 1 hr after load glucose (mmol/L) | 9.2 [8.3–9.6] | 5.9 [5.3–6.5] | <0.001 | | 2 hr after load glucose (mmol/L) | 8.0 [7.7–8.9] | 5.3 [4.8–5.8] | <0.001 | | BMI (kg/m2) | 27.16 [25.24–31.25] | 23.53 [22.72–29.00] | 0.019 | | 25(OH)D (nmol/L) | 28.5 [21.0–34.0] | 31.7 [24.0–40.0] | NS | | 25(OH)D < 50 nmol/L | 95.7% | 93.1% | NS | | Postpartum parameters (6 weeks–12 months after delivery) | | | | | Weight gain during pregnancy (kg) | 8.0 [5.0–10.5] | 14.0 [11.0–17.0] | <0.001 | | Offspring birth weight (g) | 3060 [2750–3480] | 3400 [3100–3740] | 0.016 | | Persisting glucose abnormality | 14.9% | — | — | | 25(OH)D (nmol/L) | 47.5 [40.0–53.0] | 56.5 [48.0–69.0] | 0.0041 | | 25(OH)D < 50 nmol/L | 63.8% | 34.5% | 0.012 |
|
|
Data expressed as a median [IQR] or proportions. Differences evaluated by nonparametric Mann-Whitney or Fischer’s exact test, respectively.
|
