Clinical Study

Incidence and Risk Factors of Postoperative Pulmonary Complications in Noncardiac Chinese Patients: A Multicenter Observational Study in University Hospitals

Table 4

Distribution of results of independent variables in cohort 1.

Number of patientsNumber (%) of patients with PPCsP

Age, yr<0.001
 <5967065 (9.7)
 ≥6023247 (20.3)
ASA physical status<0.001
 146420 (4.3)
 238077 (20.3)
 35413 (24.1)
 431 (33.3)
 511 (100.0)
Smokers0.001
 No75379 (10.5)
 Yes 14933 (22.1)
Respiratory infection in the last month<0.001
 No 886101 (11.4)
 Yes 1611 (68.8)
Diabetes0.001
 No 84697 (11.5)
 Yes 5615 (26.8)
COPD<0.001
 No 890106 (11.9)
 Yes 126 (50.0)
Cirrhosis0.014
 No 895109 (12.2)
 Yes 73 (42.9)
Stroke/transient ischaemic attack0.001
 No 887106 (12.0)
 Yes 156 (40.0)
Preoperative antibiotic use<0.001
 No 29819 (6.4)
 Yes 60493 (15.4)
Preoperative SpO2, %<0.001
 ≥9684592 (10.9)
 <965720 (35.1)
Preoperative anemia0.007
 No 83797 (11.6)
 Yes 6515 (23.1)
Preoperative LOS, d0.002
 <21265 (4.0)
 ≥2776107 (13.8)
Surgery site<0.001
 Peripheral62036 (5.8)
 Abdominal24356 (23.0)
 Intrathoracic3920 (51.3)
Anesthesia<0.001
 Regional23810 (4.2)
 General664102 (15.4)
Intraoperative nasogastric tube<0.001
 No 84785 (10.0)
 Yes 5527 (49.1)
Intraoperative bladder catheter<0.001
 No 46628 (6.0)
 Yes 43684 (19.3)
Intraoperative central venous catheter<0.001
 No 82185 (10.4)
 Yes 8127 (33.3)
Intraoperative blood loss, mL<0.001
 <10063632 (5.0)
 ≥10026680 (30.1)
Intraoperative blood transfusion<0.001
 No 875102 (11.7)
 Yes 2710 (37.0)
Duration of surgery, h<0.001
2 h65947 (7.1)
2 to 3 h13227 (20.5)
3 h11138 (34.2)
Postoperative SpO2, %<0.001
 ≥96891101 (11.3)
 <961111 (100.0)
Postoperative leucocyte, 109/L<0.001
462 (33.3)
 4–1066547 (7.1)
1023163 (27.3)
Postoperative anemia0.009
 No 79390 (11.3)
 Yes 10922 (20.2)
Postoperative fasting blood glucose, mmol/L<0.001
 ≤6.177850 (6.4)
 >6.112462 (50.0)
Postoperative creatinine, μmol/L<0.001
11587299 (11.4)
1153013 (43.3)
Postoperative albumin, g/L<0.001
 <3524485 (34.8)
 ≥3565827 (4.1)
Postoperative ventilation<0.001
 No87897 (11.0)
 Yes2415 (62.5)
Postoperative vasoactive drug<0.001
 No 893105 (11.8)
 Yes 97 (77.8)

Smoking: defined as patients who smoked up to 1 year before surgery; Anemia: defined as hemoglobin <100 g/L.
PPCs: postoperative pulmonary complications; ASA: American society of anesthesiologists; COPD: chronic obstructive pulmonary disease; SpO2: saturation of peripheral oxygen; LOS: length of stay.