Neuronal Nitric Oxide Synthase Is Dislocated in Type I Fibers of Myalgic Muscle but Can Recover with Physical Exercise Training

Table 1

Quantification of immunohistochemical stainings.

	Fiber type percentage (%)		nNOS intensity (%)				Cross-sectional area (m^2)
	Type I	Type II	nNOS^−	nNOS^+	nNOS^++	nNOS^sp	Average	nNOS^− fibers
CON = 18	63.3 ± 11	36.7 ± 11	25.3 ± 7	24.4 ± 8	50.2 ± 8	12.8 ± 8	5166 ± 1026	5950 ± 1309^b
MYA = 41	65.8 ± 11	34.2 ± 11	26.4 ± 10	27.2 ± 14	46.4 ± 12	18.8 ± 12^a	5149 ± 997	6104 ± 1415^b
REF = 7
Before	63.0 ± 10	37.0 ± 10	20.1 ± 7	39.4 ± 25	40.5 ± 18	15.4 ± 9	5362 ± 629	5995 ± 505^b
After	64.1 ± 15	35.9 ± 15	28.6 ± 8	30.0 ± 17	41.3 ± 14	14.1 ± 10	5221 ± 989	6783 ± 1556^b
GFT = 13
Before	67.2 ± 11	32.8 ± 11	31.5 ± 11	26.6 ± 11	41.9 ± 13	17.0 ± 11	5362 ± 525	6215 ± 1776^b
After	65.6 ± 13	34.4 ± 13	30.8 ± 12	26.9 ± 11	42.9 ± 13	13.1 ± 14	5249 ± 1935	6106 ± 1437^b
SST = 16
Before	66.0 ± 12	34.0 ± 12	22.4 ± 7	24.8 ± 7	52.9 ± 7	18.1 ± 12	4956 ± 1417	6211 ± 1489^b
After	64.3 ± 13	35.7 ± 12	23.7 ± 9	25.9 ± 9	50.4 ± 9	12.0 ± 12^c	5300 ± 1805	6123 ± 1192^b

Significant increase in nNOS^sp in MYA compared to CON (). ^bSignificant increase in CSA^nNOS− compared to CSA^avarage (). ^cSignificant decrease from before to after training ().
No nNOS in the sarcolemma (nNOS⁻), reduced nNOS in the sarcolemma (nNOS⁺), normal nNOS in the sarcolemma (nNOS⁺⁺), and nNOS in the sarcoplasm (nNOS^sp).