Candesartan Mediated Amelioration of Cisplatin-Induced Testicular Damage Is Associated with Alterations in Expression Patterns of Nephrin and Podocin

Figure 4

Apoptotic features in the testes of rats following treatment with cisplatin and/or candesartan. (a) Representative findings of TUNEL staining in rat testes. (b) The numbers of TUNEL-positive cells and total germ cells in 100 randomly selected tubules in one slide per animal were counted. Apoptotic index, defined as the percentage of TUNEL-positive cells, was then calculated for each slide. Each column represents the mean value with standard deviation. ^†, , and differ from Group 1, Group 3, and Group 5, respectively ().

(a)

(b)