Systematic Analysis and Prediction of In Situ Cross Talk of O-GlcNAcylation and Phosphorylation

Table 3

Performance evaluation.

Classifier	Level	Sp (%)	Sn (%)	ACC (%)	Pre (%)	MCC (%)
Phos-based	High	94.8	70.0	88.3	83.8	69.0
	Medium	90.0	77.8	86.7	74.2	66.8
	Low	85.0	82.0	84.2	66.9	63.2
YinOYang 1		75.5	42.7	68.9	67.5	32.7
O-GlcNAc-based	High	94.9	50.4	83.0	78.8	63.3
	Medium	90.0	57.3	81.2	67.9	50.0
	Low	85.2	70.2	81.0	63.3	53.5
YinOYang 2		71.2	42.7	56.8	59.6	14.8

For YinOYang 1 and YinOYang 2, we used the same method to evaluate the performance of YinOYang while the test sets were different. For YinOYang 1, the test dataset is the same with that used for phos-based classifier and, for YinOYang 2, the test dataset is the same with that used for O-GlcNAc-based classifier.