The HDAC Inhibitor Vorinostat Diminishes the In Vitro Metastatic Behavior of Osteosarcoma Cells

Figure 4

Differences in gene expression of K7M2 cells with vorinostat (50 μM) treatment. The expressions of mTOR, ALDH, and PGC-1 were all decreased, whereas Notch1 expression did not change and LC3 expression increased with vorinostat treatment.