Transdermal Nicotine Application Attenuates Cardiac Dysfunction after Severe Thermal Injury

Figure 4

Systole. (a) and (b): duration of systole. The systole duration increased in experimental burn group (black versus white bar, ). The BURN + NICOTINE groups revealed significantly lower duration of systole values than their burn alone counterparts (striped versus black bar, ). (c) and (d): maximum increase of blood pressure per second (contractility). Reduced contractility was found for the BURN group (black versus white bar, ). Nicotine administration showed restored contractility (striped versus black bar, ). All values are expressed as mean + SD. Each bar represents experiments.

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