Transdermal Nicotine Application Attenuates Cardiac Dysfunction after Severe Thermal Injury

Figure 5

Diastole. (a) and (b): duration of diastole. The BURN group revealed significantly shorter diastole duration than the CTRL group (black versus white bar, ). After posttraumatic nicotine application this effect is slightly reduced although differences were not statistically relevant (striped versus black bar, not significant). (c) and (d): minimum blood pressure difference per second (relaxation). Note that the scale is negative. The difference between the BURN and BURN + NICOTINE animals is marked (black versus striped bars, ). Interestingly, both SHAM and BURN + NICOTINE groups display higher values than the control group. All results are expressed as mean + SD. Each bar represents experiments.

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