Research Article
The Power of Phase I Studies to Detect Clinical Relevant QTc Prolongation: A Resampling Simulation Study
Figure 4
Time course of moxifloxacin plasma concentration and placebo corrected change from baseline of QTcF for each of the three studies, based on all subjects included. (a) Study 1, (b) Study 2, and (c) Study 3.
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(b) |
(c) |