Prokineticin 2 Upregulation in the Peripheral Nervous System Has a Major Role in Triggering and Maintaining Neuropathic Pain in the Chronic Constriction Injury Model

<div>Confocal images of representative sections of longitudinally sliced sciatic nerve, proximal and distal to the lesion, immunostained for PROK2 (green) and NF200 (red) from sham-operated, CCI-saline and CCI-PC1 mice at 10 dpi. Scale bar: 30 μm. PROK2-green signal was localized between NF200 positive fibers in CCI-saline mice but was not found in the nerve from CCI-PC1 mice.</div>

BioMed Research International

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Figure 8: Prokineticin 2 Upregulation in the Peripheral Nervous System Has a Major Role in Triggering and Maintaining Neuropathic Pain in the Chronic Constriction Injury Model 

Figure 8 | Prokineticin 2 Upregulation in the Peripheral Nervous System Has a Major Role in Triggering and Maintaining Neuropathic Pain in the Chronic Constriction Injury Model 