PVT1: A Rising Star among Oncogenic Long Noncoding RNAs

Figure 4

PVT1 expression in cancer. (a) Barplots of mean PVT1 expression in cancer versus normal tissues from the Cancer Genome Atlas [22]. Values are ordered by decreasing abundance in cancer. -axis: normalized expression value (FPKM). -axis: TCGA tissues. (b) Barplots of mean PVT1 expression in TCGA cancer tissues, ordered by decreasing abundance. -axis and -axis: same as in (a). (c) Scatterplot of the MYC versus PVT1 expression values across all the samples analyzed in (a-b). The Pearson correlation () and the corresponding value are shown. Abbreviations: acc: adrenocortical carcinoma; blca: bladder urothelial carcinoma; lgg: brain lower grade glioma; brca: breast invasive carcinoma; cesc: cervical squamous cell carcinoma and endocervical adenocarcinoma; chol: cholangiocarcinoma; coad: colon adenocarcinoma; gbm: glioblastoma multiforme; hnsc: head and neck squamous cell carcinoma; kich: kidney chromophobe; kirc: kidney renal clear cell carcinoma; kirp: kidney renal papillary cell carcinoma; lihc: liver hepatocellular carcinoma; luad: lung adenocarcinoma; lusc: lung squamous cell carcinoma; dlbc: lymphoid neoplasm diffuse large B-cell lymphoma; meso: mesothelioma; ov: ovarian serous cystadenocarcinoma; paad: pancreatic adenocarcinoma; pcpg: pheochromocytoma and paraganglioma; prad: prostate adenocarcinoma; read: rectum adenocarcinoma; sarc: sarcoma; skcm: skin cutaneous melanoma; tgct: testicular germ cell tumors; thym: thymoma; thca: thyroid carcinoma; ucs: uterine carcinosarcoma; ucec: uterine corpus endometrial carcinoma; uvm: uveal melanoma.

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