Roles of Osteopontin Gene Polymorphism (rs1126616), Osteopontin Levels in Urine and Serum, and the Risk of Urolithiasis: A Meta-Analysis

Table 3

Meta-analysis results of the association between OPN C6982T polymorphism and urolithiasis risk.

		Sample size	CT versus CC		TT versus CC		CT/TT versus CC		TT versus CT/CC
Total	5	1681	2.49 (1.01–6.17)	0.000	2.71 (1.02–7.15)	0.000	2.31 (1.10–4.85)	0.000	1.64 (0.95–2.81)	0.024
Ethnicity
Asian	2	1127	2.75 (0.15–51.89)	0.001	3.05 (0.17–53.74)	0.001	2.91 (0.16–52.75)	0.000	1.14 (0.89–1.46)	0.329
Turkish	3	554	2.69 (1.26–5.75)	0.052	2.88 (1.14–7.30)	0.070	2.50 (1.72–3.63)	0.669	2.08 (0.76–5.67)	0.030
Genotyping
PCR-RFLP	3	1359	2.07 (0.56–7.67)	0.000	1.28 (0.64–2.54)	0.108	1.76 (0.68–4.57)	0.001	1.11 (0.88–1.42)	0.549
PCR-SSCP	2	322	3.97 (0.47–33.24)	0.014	7.66 (3.28–17.89)	0.384	4.58 (0.70–30.18)	0.024	2.86 (1.12–7.33)	0.134

Number of studies.
^b value of test for heterogeneity.