Review Article

Roles of Osteopontin Gene Polymorphism (rs1126616), Osteopontin Levels in Urine and Serum, and the Risk of Urolithiasis: A Meta-Analysis

Table 4

Summary of SMD and 95% CI for associations between OPN level and urolithiasis risk.

PolymorphismSubgroupSample sizeSMD (95% CI) value heterogeneity

UrineAll71754−0.55 (−1.30–0.20)0.151<0.0001
Large sample size215220.78 (−0.89 to −0.67)<0.00010.749
Asian populations51671−0.65 (−1.61–0.31)0.182<0.0001

SerumAll3 12701.47 (−1.89 to −1.04)<0.00010.01

The number of studies.