Association between AKT1 Gene Polymorphism rs2498794 and Smoking-Related Traits with reference to Cancer Susceptibility

Table 2

Comparisons of clinical data between presence/absence of cancer history.

		Minimum	Maximum	Mean	SD	Median	Statistic^a		Direction of association
Sex	962						9.88	0.00167	Higher cancer risk in males
Cancer (male/female)	148/63
Control (male/female)	437/314
Age (years)	970						74228.50	0.06514
Cancer	214	64	88	74.12	5.73	74.00
Control	756	60	94	73.43	5.89	73.00
Height (cm)	968						71176.50	0.01035	Higher height in cancer subjects
Cancer	213	140	175	158.20	7.84	160.00
Control	755	130	180	156.45	8.92	157.00
Weight (kg)	967						82386.00	0.56215
Cancer	213	30	101	54.53	10.19	54.00
Control	754	30	90	54.77	9.90	54.00
Smoking history	971						3.10	0.07831
Cancer (ever-smokers/never-smokers)	92/122
Control (ever-smokers/never-smokers)	377/380
Smoking period (year)	501						20624.50	0.07276
Cancer	122	10.00	64.00	42.45	13.63	46.00
Control	379	1.00	68.00	39.71	14.64	44.00
CPD^b	501						20187.00	0.03041	Higher CPD in cancer subjects
Cancer	122	2.50	80.00	23.75	15.10	20.00
Control	379	1.00	100.00	20.77	12.90	20.00
Brinkman (smoking) index (BI)	500						19746.50	0.01700	Higher BI in cancer subjects
Cancer	122	100.00	3360.00	1001.64	708.25	860.00
Control	378	9.00	3480.00	809.38	547.47	680.00

U value for Mann-Whitney test and value for test.
^bCigarettes smoked per day.
P < 0.05.