Research Article

Molecular PET Imaging of Cyclophosphamide Induced Apoptosis with 18F-ML-8

Figure 1

(a) Chemical synthesis of ML-8 (9) and its precursor (7) starting from 3-bromo-propanol and diethyl malonate. (b) Radiosynthesis of 18F-ML-8 from the precursor (7). O-TBDMS = O-tert butyl dimethyl silyl; O-Et = O-ethyl; O-Ms = O-mesyl.
(a)
(b)