A Comprehensive Systems Biological Study of Autophagy-Apoptosis Crosstalk during Endoplasmic Reticulum Stress

Figure 3

The time course profile of cell treatment with respect to low and high levels of DTT. HepG2 cells were treated with (left panel) low (1 mM) and (right panel) high (10 mM) level of DTT. (a) The autophagy (LC3II, p62) and apoptosis markers (procaspase-3, cleaved PARP) were followed in time by immunoblotting. (b) The percentage of apoptotic cells was calculated by Annexin-V-FLUOS kit (errors bars represent standard deviation).

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