A Comprehensive Systems Biological Study of Autophagy-Apoptosis Crosstalk during Endoplasmic Reticulum Stress

Figure 8

Analyzing the effect of transient treatment with mathematical method. 50 single cell simulations were done at all different time points when the ER stressor was washed out from 15 to 105 min (S0 = 10). The reversibility of apoptosis induction was checked after 120 min of depletion of ER stressor.