Research Article

Role of B7-H4 siRNA in Proliferation, Migration, and Invasion of LOVO Colorectal Carcinoma Cell Line

Table 2

Effects of B7-H4 siRNA on the mRNA expression of CXCL12 and CXCR4.

GroupCXCL12 (%)CXCR4 (%)

Control4.90 0.00388.93 0.0163
Mock4.66 0.00847.44 0.0043
B7-H4 siRNA 1.54 0.00422.48 0.0035

After LOVO cells were treated with B7-H4 siRNA transfection for 6 h; the RNA expression of CXCL12 and CXCR4 was detected by RT-PCR. p < 0.01 compared with the control group; p < 0.01 compared with the mock group; data are expressed as the mean ± SD, .