Review Article

Oxidative Stress Control by Apicomplexan Parasites

Table 1

Predicted antioxidant enzymes according to the genome databases of Babesia and Cryptosporidium.

ProteinsAbbr.B. bovis B. equi C. hominis C. parvum References

Directly dealing with prooxidants
 Glucose-6-phosphate dehydrogenaseBBOV_IV001600BEWA_012440A[122, 123]
 Superoxide dismutase (SOD1) FeSODB1U70131BEWA_043090XM_660499AY599065[124, 125]
 PeroxiredoxinPrx1BEWA_033010[23, 28]
Glutathione system
 Glutathione peroxidase 1XM_663205.1XM_626631.1[58, 68, 126]
 Glutathione reductase[68]
 Glutathione synthaseXP_001610411XM_004829930[122, 123]
 GlutaredoxinGrxBBOV_IV00432023BEWA_031250XM_660840XM_627733[58, 122, 123, 126]
Thioredoxin system
 ThioredoxinTrxBBOV_II003650BEWA_047060XP_626144[26, 126]
 Thioredoxin peroxidase 1AK440717BEWA_001220XM_660495GQ388272[72]
 Thioredoxin reductaseTrxRBBOV_I002190XM_004831637GQ388271AY145120[26]