BioMed Research International

Review Article

Oxidative Stress Control by Apicomplexan Parasites

Table 2

Antioxidant enzymes in T. gondii.
ProteinsAbbr.T. gondii CommentsStage LocalisationReferences
Directly dealing with prooxidants      
 CatalaseCATAF161267 ConstitutiveCytoplasmatic[104, 105, 107]
 Glucose-6-phosphate dehydrogenase  XP_002370586Putative   
 Superoxide dismutase (SOD1) FeSODB1AF029915Fe in the active siteTachyzoite/bradyzoiteCytoplasmatic[115]
 Superoxide dismutase (SOD2) SOD2AY176062 ConstitutiveMitochondrial[107]
 Superoxide dismutase (SOD3)SOD3AY254045 Sporulated oocystMitochondrial[107]
 PeroxiredoxinPrx1AF3057182-Cys mechanismConstitutiveCytoplasmatic[107, 127]
 PeroxiredoxinPrx2AF3972131-Cys mechanismTachyzoite/bradyzoiteCytoplasmatic[107]
 PeroxiredoxinPrx3AY2510212-Cys mechanismConstitutiveMitochondrial[107]
Glutathione system      
 Glutathione peroxidase 1  AY043228PutativeTachyzoite/bradyzoite  
 Glutathione reductase  AF041450Putative   
 Glutathione synthase  XP_002366333 Putative   
 Glutathione-S-transferase  XP_002369230Putative   
 γ-Glu-Cys synthase  XP_002368128 Putative   
 GlutaredoxinGrx1BM131493Putative   
 GlutaredoxinGrx2BM040167Putative   
Thioredoxin system      
 ThioredoxinTrxBG657266PutativeConstitutive [117]
 Thioredoxin peroxidase 1  BM039715PutativeOocyst [117]
 Thioredoxin reductase TrxRAA519618Putative