Review Article
Oxidative Stress Control by Apicomplexan Parasites
Table 2
Antioxidant enzymes in T. gondii.
| Proteins | Abbr. | T. gondii | Comments | Stage | Localisation | References |
| Directly dealing with prooxidants | | | | | | | Catalase | CAT | AF161267 | | Constitutive | Cytoplasmatic | [104, 105, 107] | Glucose-6-phosphate dehydrogenase | | XP_002370586 | Putative | | | | Superoxide dismutase (SOD1) Fe | SODB1 | AF029915 | Fe in the active site | Tachyzoite/bradyzoite | Cytoplasmatic | [115] | Superoxide dismutase (SOD2) | SOD2 | AY176062 | | Constitutive | Mitochondrial | [107] | Superoxide dismutase (SOD3) | SOD3 | AY254045 | | Sporulated oocyst | Mitochondrial | [107] | Peroxiredoxin | Prx1 | AF305718 | 2-Cys mechanism | Constitutive | Cytoplasmatic | [107, 127] | Peroxiredoxin | Prx2 | AF397213 | 1-Cys mechanism | Tachyzoite/bradyzoite | Cytoplasmatic | [107] | Peroxiredoxin | Prx3 | AY251021 | 2-Cys mechanism | Constitutive | Mitochondrial | [107] | Glutathione system | | | | | | | Glutathione peroxidase 1 | | AY043228 | Putative | Tachyzoite/bradyzoite | | | Glutathione reductase | | AF041450 | Putative | | | | Glutathione synthase | | XP_002366333 | Putative | | | | Glutathione-S-transferase | | XP_002369230 | Putative | | | | γ-Glu-Cys synthase | | XP_002368128 | Putative | | | | Glutaredoxin | Grx1 | BM131493 | Putative | | | | Glutaredoxin | Grx2 | BM040167 | Putative | | | | Thioredoxin system | | | | | | | Thioredoxin | Trx | BG657266 | Putative | Constitutive | | [117] | Thioredoxin peroxidase 1 | | BM039715 | Putative | Oocyst | | [117] | Thioredoxin reductase | TrxR | AA519618 | Putative | | | |
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