Androgen Receptor, EGFR, and BRCA1 as Biomarkers in Triple-Negative Breast Cancer: A Meta-Analysis

Table 4

Subgroup analyses based on ethnic for AR expression, EGFR expression, and BRCA1 mutation in TNBC compared with non-TNBC.

Variables	AR				EGFR				BRCA1
		OR (95% CI)				OR (95% CI)				RR (95% CI)
Total	14	0.07 (0.05–0.11)	<0.001	79%	10	6.88 (3.84–12.35)	<0.001	85%	18	5.26 (4.42–6.26)	0.14	27%
Ethnic
Asian	6	0.11 (0.06–0.21)	0.002	73%	5	9.60 (3.50–26.30)	0.01	68%	9	5.43 (4.06–7.25)	0.71	0%
Caucasian	8	0.06 (0.03–0.09)	<0.001	82%	5	5.53 (2.84–10.77)	<0.001	87%	9	5.16 (4.16–6.40)	0.02	55%

: numbers of data sets; : value of -test for heterogeneity test; indicates that there is heterogeneity and random-effect model is used to calculate pooled OR or RR and 95% CI. Otherwise, fixed-effect model is used.