Review Article
Impact of Ischemic Preconditioning on Outcome in Clinical Liver Surgery: A Systematic Review
Table 6
Outcome in clinical studies of ischemic preconditioning in liver resection with subgroup analysis of hepatic steatosis.
| | Author | Year | Study type | IPC | No IPC | % steatosis (Type) | Duration of IPC (mins) | Mean ischemic time (mins) | Outcome measures | Effect of IPC |
| | Arkadopoulous et al. [49] | 2009 | RCT | 5 | 4 | >30% (not stated) | 10 + 15 | 42 (TVE) | AST | ↓AST |
| | Clavien et al. [20] | 2003 | RCT | 7 | 6 | >25% (not stated) | 10 + 10 | 36 | AST | ↓Peak AST
(363 versus 602 UI/L) |
| | Clavien et al. [15] | 2000 | Prospective | 4 | 3 | >25% (not stated) | 10 + 10 | 30 | ALT, AST | ↓ALT/AST
(<260 UI/L each patient at day 1) |
|
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ALT, alanine aminotransferase; AST, aspartate aminotransferase; IPC, ischemic preconditioning; RCT, randomized control trial; TVE, total vascular exclusion.
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