Implication of Caspase-3 as a Common Therapeutic Target for Multineurodegenerative Disorders and Its Inhibition Using Nonpeptidyl Natural Compounds

Table 2

Binding affinity of nonpeptidyl natural compounds against caspase-3.

Compounds	Gold fitness score	X-score
Rosmarinic acid	57.38	−8.93
Curcumin	53.51	−8.14
Luteolin	51.24	−8.51
Huperzine A	51.13	−7.97
Quercetin	44.33	−6.98
Resveratrol	42.65	−6.53
Bilobalide	43.74	−6.56
EGCG	47.15	−7.02
Apigenin	41.32	−6.97
Berberine	40.56	−5.48
Chitosan	37.67	−5.97