TOP2A Amplification and Overexpression in Hepatocellular Carcinoma Tissues

Table 2

Clinicopathological features of HCC patients ( = 40).

Patients	(%)
Age (years)
<50	18 (45.0)
≥50	22 (55.0)
Range	35–94
Mean	52.5
Median	51
Sex
Male	35 (87.5)
Female	5 (12.5)
HBsAg
Negative	12 (30.0)
Positive	28 (70.0)
AFP
<500 ng/mL	24 (60.0)
≥500 ng/mL	13 (32.5)
Unknown	3 (7.5)
Tumor size
<5 cm	14 (35.0)
≥5 cm	26 (65.0)
TP53 expression
Negative	21 (52.5)
Positive	18 (45.0)
Unknown	1 (2.5)
Ki-67 expression
<10%	9 (22.5)
≥10%	30 (75.0)
Unknown	1 (2.5)

HBsAg: hepatitis B surface antigen; AFP: alpha fetoprotein; HCC: hepatocellular carcinoma; TP53: tumor protein p53.