Managing Hypercapnia in Patients with Severe ARDS and Low Respiratory System Compliance: The Role of Esophageal Pressure Monitoring—A Case Cohort Study
Table 3
Respiratory and hemodynamic parameters on baseline and 1 hour after intervention guided by esophageal balloon measurements.
Baseline before intervention
One hour after intervention
value
PaCO2 (mmHg)
108.33 ± 25.65
64.5 ± 16.89
0.003
PH
7.01 ± 0.08
7.20 ± 0.08
<0.001
FiO2 (%)
66.66 ± 16.32
53.33 ± 5.16
0.08
PEEP
13.66 ± 2.16
10.83 ± 5.45
0.18
P/F ratio (mmHg)
144.25 ± 54.15
158.66 ± 30.11
0.45
Respiratory rate
23.7 ± 6.8
21.7 ± 4.3
0.3
Minute ventilation (L/min)
5.6 ± 1.8
9.1 ± 1.4
<0.001
Inspiratory pressure
16.66 ± 2.58
24.16 ± 2.04
0.007
EITP pressure
13.68 ± 8.69
16.76 ± 4.76
0.18
EETP pressure
1.5 ± 5.96
−0.25 ± 4.32
0.19
Plateau pressure
28.76 ± 2.77
32.76 ± 7.20
0.29
Tidal volume (in mL)
244.16 ± 69.88
435.0 ± 103.7
<0.001
Tidal volume (in mL/kg IBW)
3.96 ± 0.92
7.07 ± 1.21
<0.001
Total respiratory system compliance
16.56 ± 5.9
19.99 ± 5.73
0.11
Lung compliance*
23.09 ± 8.66
26.717 ± 9.67
0.29
Chest wall compliance*
40.5 ± 63.5
81.1 ± 124
0.168
Cardiac index (L/min/m2)
2.98 ± 0.66
3.21 ± 0.57
0.25
Compliance in mL/cmH2O. EITP: end inspiratory transpulmonary pressure, EETP: end expiratory transpulmonary pressure, and PEEP: positive end expiratory pressure.
