Research Article
Transcriptional Pathways Associated with Skeletal Muscle Changes after Spinal Cord Injury and Treadmill Locomotor Training
Table 2
Five most significantly activated pathways for each comparison of the study.
| Group/comparison | 3 days | 8 days | 14 days |
| No treadmill training versus control | Protein ubiquitination pathway | Mitochondrial dysfunction | Mitochondrial dysfunction | Mitochondrial dysfunction | Valine, leucine, and isoleucine degradation | Synthesis and degradation of ketone bodies | Oxidative phosphorylation | Propanoate metabolism | Oxidative phosphorylation | Regulation of eIF4 and p70S6K signaling | Butanoate metabolism | Citrate cycle | Ubiquinone biosynthesis | Pyruvate metabolism | Ephrin receptor signaling |
| Treadmil training versus no training | | Protein ubiquitination pathway | Estrogen receptor signaling | | Amyloid processing | EIF2 signaling | | BMP signaling pathway | Regulation of eIF4 and p70S6K signaling | | Role of BRCA1 in DNA damage response | Glutamate metabolism | | Hereditary breast cancer signaling | Granzyme B signaling |
|
|