Evaluation of Liver Fibrosis Using Texture Analysis on Combined-Contrast-Enhanced Magnetic Resonance Images at 3.0T

Table 1

Selection criteria.

Inclusion criteria

Exclusion criteria

(i) Age >18 years; (ii) Newly diagnosed HCV infection, without clinically overt cirrhosis; (iii) Recent or planned biopsy^1; (iv) Willing and able to undergo CCE MRI exam within 30 days of biopsy; (v) Willing and able to undergo phlebotomy for estimated GFR determination within 30 days of biopsy

(i) Estimated GFR <60 mL/mL ( potential subjects); (ii) Imaging not performed within 30 days of biopsy (); (iii) Nondiagnostic biopsy or trichrome slide unavailable (); (iv) Contraindication to MR exam ()^2; (v) Lack of intravenous access (); (vi) History of severe allergic reaction or anaphylaxis (); (vii) History of liver diseases other than HCV including iron overload (); (viii) Severe claustrophobia (); (ix) Pregnant or nursing mother ()

Biopsies were performed for clinical care. Due to intraorbital shrapnel. GFR: glomerular filtration rate. Parenthesis () contains the number of potential subjects excluded for the criterion.