Research Article

Evaluation of Liver Fibrosis Using Texture Analysis on Combined-Contrast-Enhanced Magnetic Resonance Images at 3.0T

Table 5

Receiver operating characteristics (texture versus %-collagen).

Classification CutoffArea under curveSensitivitySpecificityAccuracy

<5% versus ≥5%9.3150.806 [0.680 0.932]0.688 [0.527 0.848]0.857 [0.674 1.000]0.739 [0.592 0.850]
<10% versus ≥10%9.8070.742 [0.589 0.895]0.722 [0.515 0.929]0.679 [0.506 0.852]0.696 [0.547 0.815]
<15% versus ≥15%10.5000.894 [0.758 1.000]0.900 [0.714 1.000]0.750 [0.609 0.891]0.783 [0.638 0.884]
<20% versus ≥20%11.2340.950 [0.826 1.000]1.000 [0.907 1.000]0.825 [0.707 0.943]0.848 [0.686 0.916]

Cutoff: the operating point on the ROC curve closest to (), the point of maximum sensitivity and specificity. —95% confidence interval. The mismatch between the texture-based cutoff and the histologic classification threshold is expected (see text).