Association of Polymorphisms of the Receptor for Advanced Glycation End Products Gene and Susceptibility to Sporadic Abdominal Aortic Aneurysm
Table 4
A comparison between the baseline characteristics of the RAGE G82S genotypes and alleles in the AAA patient and control groups.
Characteristics
AAA patient group
Control group
value
value
Genotype (%)
Allele (%)
Genotype (%)
Allele (%)
GG
GS
SS
G
S
GG
GS
SS
G
S
Age
≥70 years
103 (47.9)
95 (44.2)
17 (7.9)
301 (70.0)
129 (30.0)
136 (57.9)
84 (35.7)
15 (6.4)
356 (75.7)
114 (24.3)
0.11
0.052
<70 years
84 (50.6)
60 (36.1)
22 (13.3)
228 (68.7)
104 (31.3)
122 (60.7)
65 (32.3)
14 (7.0)
309 (76.9)
93 (23.1)
0.092
0.058
Gender
Male
140 (47.9)
119 (40.8)
33 (11.3)
399 (68.3)
185 (31.7)
131 (59.3)
75 (33.9)
15 (6.8)
337 (76.2)
105 (23.8)
Female
47 (52.8)
36 (40.4)
6 (6.7)
130 (73.0)
48 (27.0)
127 (59.1)
74 (34.4)
14 (6.5)
328 (76.3)
102 (23.7)
0.59
0.40
Smoking
Yes
91 (44.2)
95 (46.1)
20 (9.7)
277 (67.2)
135 (32.8)
87 (60.0)
50 (34.5)
8 (5.5)
224 (77.2)
66 (22.8)
0.020
0.008
No
96 (54.9)
60 (34.3)
19 (10.9)
252 (72.0)
98 (28.0)
171 (58.8)
99 (34.0)
21 (7.2)
441 (75.8)
141 (24.2)
0.37
0.20
Diabetes
Yes
37 (41.6)
43 (48.3)
9 (10.1)
117 (65.7)
61 (34.3)
51 (59.3)
29 (33.7)
6 (7.0)
131 (76.2)
41 (23.8)
0.070
0.082
No
150 (51.4)
112 (38.4)
30 (10.3)
412 (70.5)
172 (29.5)
207 (59.1)
120 (34.3)
23 (6.6)
534 (76.3)
166 (23.7)
0.088
0.060
Hypertension
Yes
69 (46.9)
62 (42.2)
16 (10.9)
200 (68.0)
94 (32.0)
91 (58.7)
54 (34.8)
10 (6.5)
236 (76.1)
74 (23.9)
0.093
0.056
No
118 (50.4)
93 (39.7)
23 (9.8)
329 (70.3)
139 (29.7)
167 (59.4)
95 (33.8)
19 (6.8)
429 (76.3)
133 (23.7)
0.10
0.069
: value of the difference in alleles between the case and control groups; : value of the difference in genotype between the case and control groups.
aAdjusted for age, gender, smoking, hypertension, diabetes mellitus, and dyslipidemia.
b values under 0.05 were indicated in bold font.
