Antidepressant-Like Effect of the Leaves of Pseudospondias microcarpa in Mice: Evidence for the Involvement of the Serotoninergic System, NMDA Receptor Complex, and Nitric Oxide Pathway

Figure 5

Effects of PME (100 mg kg⁻¹), FLX (10 mg kg⁻¹), and DES (10 mg kg⁻¹) on the number of 5-HTP-induced head twitches in mice. Data are expressed as mean ± SEM (). The lower and upper margins of the boxes represent the 25th and 75th percentiles, with the extended arms representing the 10th and 90th percentiles, respectively. The median is shown as the horizontal line within the box. ; compared with the saline-treated control (one-way ANOVA followed by Newman-Keuls post hoc test).