Hematopoietic Stem and Progenitor Cells Can Be Enriched by Implanting Biomaterial into Spatium Intermusculare

Figure 5

Granulocyte colony-stimulating factor (G-CSF) increased hematopoietic stem and progenitor cells (HSPCs) in the migrating cells (MCs). (a) Cell number in MCs after G-CSF administration. (b) G-CSF in the sponge reduced the time of implantation and increased the number of MCs. (c) G-CSF in the sponge significantly increased the frequency of CFU, CD34⁺, Sca-1⁺, and CD34⁺Sca-1⁺ cells in the total MCs. (d) G-CSF in the sponge significantly increased the frequency of colonies in the total MCs. The bars represented mean ± SD (); versus control (4 days), ^# versus control (12 days).

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