Puerarin Inhibits oxLDL-Induced Macrophage Activation and Foam Cell Formation in Human THP1 Macrophage

Figure 5

Effect of puerarin on oxLDL-induced early apoptotic cells in human THP1 macrophages. oxLDL (50 μg/mL) significantly increased early apoptotic cells of macrophage (Annexin V-positive and PI-negative cells as indicated by arrow) determined by flow cytometry analysis, and treatment with puerarin (100 μg/mL) significantly reduced oxLDL-induced apoptotic cells. (a): representative original trace of flow cytometry; (b): the quantitative analysis of early apoptotic cells of macrophages in bar graphs. versus control; versus oxLDL. .

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