R990G Polymorphism of Calcium Sensing Receptor Gene Is Associated with High Parathyroid Hormone Levels in Subjects with Vitamin D Deficiency: A Cross-Sectional Study

Table 3

Frequency and distribution of plasma iPTH, serum calcium, and serum 25OHD levels in CaSR SNP, R990G genotypes.

Analytes	R990G polymorphism			value
	AA ( = 112)	AG ( = 12)	GG ( = 16)
Plasma iPTH (pg/mL)	90.4 ± 58.5	86.1 ± 58	148.7 ± 66.4	0.008
Serum calcium (mg/dL)	9.1 ± 0.3	9.1 ± 0.3	8.5 ± 0.4	0.002
Serum 25OHD (ng/mL)	8.3 ± 12.1	6.7 ± 7.1	11 ± 8.2	0.37

One way analysis of variance was performed with post hoc analysis by Tukey’s test.
Tukey’s test showed mean difference of iPTH and calcium levels were significantly different in GG genotype.
value < 0.05 was considered statistically significant.