Research Article
A Kinetic-Model-Based Approach to Identify Malfunctioning Components in Signal Transduction Pathways from Artificial Clinical Data
Table 2
The rank of the possibility of the reactions whose downregulation causes the abnormal profiles shown in Figure
6(b).
| Rank | Reaction index | | (STAT3N-STAT3N) | (SOCS3) |
| 1 | 44 | 0.98 | 0.98 | 0.98 | 2 | 43 | 0.77 | 0.97 | 0.0017 | 3 | 40 | 0.77 | 0.97 | 0.0017 | 4 | 47 | 0.46 | 0.015 | 0.88 | 5 | 46 | 0.42 | 0.014 | 0.94 | 6 | 36 | 0.29 | 0.27 | 0.34 | 7 | 41 | 0.29 | 0.0040 | 0.86 | 8 | 42 | 0.25 | 0.41 | 0.036 | 9 | 34 | 0.22 | 0.20 | 0.27 | 10 | 11 | 0.17 | 0.15 | 0.24 |
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