A Kinetic-Model-Based Approach to Identify Malfunctioning Components in Signal Transduction Pathways from Artificial Clinical Data

Table 7

Rank of the possibility of preexisting molecules whose upregulation causes the abnormal profiles shown in Figure 9(c).

Number	Molecule index
1	Cytoplasmic IκBαNF-κB	0.98	0.048	30
2	TNFR1	0.46	0.00	0.00
3	Free nuclear NF-κB	0.25	0.0011	0.49
4	Free cytoplasmic IκBα	0.24	0.0014	0.50
5	Nuclear IκBαNF-κB	0.24	0.0013	0.45