A Kinetic-Model-Based Approach to Identify Malfunctioning Components in Signal Transduction Pathways from Artificial Clinical Data

Table 8

Rank of the possibility of preexisting molecules whose downregulation causes the abnormal profiles shown in Figure 9(d).

Number	Molecule index
1	TRADD	0.98	0.0014	0.94
2	TRAF2	0.67	0.00062	0.34
3	RIP-1	0.60	0.00048	0.25
4	Cytoplasmic A20	0.50	0.0013	0.47
5	Nuclear IκBαNF-κB	0.50	0.0013	0.46